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Knuckle pads : ウィキペディア英語版 | Knuckle pads
Knuckle pads (also known as "Heloderma", meaning similar to the skin of the Gila monster lizard for which it is named) are circumscribed, keratotic, fibrous growths over the dorsa of the interphalangeal joints.〔Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). Page 990. McGraw-Hill. ISBN 0-07-138076-0.〕 Knuckle pads are well-defined, round, plaque-like, fibrous thickening that may develop at any age, and grow to be 10 to 15mm in diameter in the course of a few weeks or months, then go away over time .〔James, William; Berger, Julia Meakin, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. ISBN 0-7216-2921-0.〕 Knuckle pads are sometimes associated with Dupuytren's contracture and camptodactyly,〔 and histologically, the lesions are fibromas.〔 Knuckle pads are generally non-responsive to treatment, including corticosteroids, and tend to recur after surgery; however, there has been some effectiveness with intralesional fluorouracil.〔Weiss, Eduardo; Amini, Sadegh (2007). "A Novel Treatment for Knuckle Pads With Intralesional Fluorouracil". ''Arch Dermatol.'' 143(11). Pages 1447-1462. http://archderm.jamanetwork.com/article.aspx?articleid=654437〕 ==See also==
*Skin lesion * List of cutaneous conditions
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Knuckle pads」の詳細全文を読む
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